Southampton sacked manager Nathan Jones on Sunday.
Jones' dismissal comes less than 24 hours after the team's 2-1 loss to Wolves on Saturday.
Chris Cohen and Alan Sheeha, the first team coaches, were also sacked by the Premier League club.
The club announced this in a statement on its website.
"Southampton Football Club can confirm that it has parted ways with Men's First Team Manager Nathan Jones," said the statement.
"First Team Coaches Chris Cohen and Alan Sheehan have both left the club.
"First team head coach Rubén Sellés will oversee training and prepare the team for the game against Chelsea next weekend."