Long queues have formed at the few stations still selling fuel, with people buying in jerricans for domestic and commercial use.
The situation worsened on Tuesday, with fuel prices ranging from N400 to N550 at the discretion of marketers.
While major stations along MCC and Murtala Mohammed Way sold fuel for N400 to N500, those in Calabar South charged between N500 and N550 despite the long queues.
Some stations ceased selling fuel based on directives from management, uncertain about what would follow the removal of the subsidy.
Taxi driver Mr Okon Etim managed to buy fuel for N280 at a station on Atu Street, but black market sellers charged between N650 and N750.
Although petroleum product scarcity has occurred, transport fares within the Calabar metropolis have remained stable between N100 and N200, depending on the route and distance. The effects of the fuel subsidy removal are causing inconvenience and financial strain for the residents of Cross River State.