While Alex Iwobi's Everton travels to face Bournemouth, Wilfred Ndidi and Kelechi Iheanacho will take on Newport County at the King Power Stadium.
After overcoming Grimsby to advance to the third round, Taiwo Awoniyi and Emmanuel Dennis are scheduled to play Tottenham.
Joe Aribo will play for Southampton against Sheffield at home in the third-round match, while Frank Onyeka's Brentford will travel to Gillingham.
While Wolves host Leeds, West Ham will play Blackburn Rovers. While Liverpool will play Derby County, Manchester United will play Aston Villa.
Stevenage will face Charlton, Newcastle will host Crystal Palace, and Arsenal will play host to Brighton.
See full fixtures below;
- Leicester City vs. Newport County
- West Ham vs. Blackburn Rovers
- Wolves vs. Leeds United
- Nottingham Forest vs. Spurs
- Man Utd vs. Aston Villa
- Bournemouth vs. Everton
- Liverpool vs. Derby County
- Burnley vs. Crawley
- Bristol City vs. Lincoln City
- Man City vs. Chelsea
- Stevenage vs. Charlton
- MK Dons vs. Morecambe
- Newcastle vs. Crystal Palace
- Arsenal vs. Brighton
- Brentford vs. Gillingham
- Southampton vs. Sheffield